*These statements have not been evaluated by the Food and Drug Administration. Ingredient information is not intended to diagnose, treat, cure, or prevent any disease.
Material Name(s): Trans- Menaquinone-7, MK7
Vitamin K is an essential vitamin needed for cardiovascular, bone and liver health. Vitamin K2 is more effective than vitamin K1, the form found in plants, for these specific health effects.
Vitamin K2 MK-7 is superior to MK-4 regarding biological activity and half-life in the body. MK-7 has a half-life of about 72 hours whereas it is only about 1.5 hours for MK-4. Therefore, MK-7 remains biologically active in the body longer and allows for better bodily distribution and activation of extra-hepatic K2-dependent proteins such as osteocalcin and matrix gla-protein (MGP). These differences arise from the differences in the distribution and breakdown of the two MK forms. MK-4 is mainly transported in the blood via triglyceride-rich lipoproteins whereas low-density lipoproteins transport MK-7. MK-7 reaches bones and vessel walls easier than MK-4. The daily requirement of MK-7 is much lower compared to MK-4 (around 90-120 μg/day for MK-7 and 45,000 μg three times a day for MK-4.)
- Country of origin: Denmark
- Starting material: Pharmaceutical synthesis vitamin K2 from geriniol
- Trans isomer