Probiotic 3™


A unique, clinically tested, probiotic formula

  • Promotes healthy gut flora
  • Helps with digestion and immune system support
  • Supports a healthy gastrointestinal tract
Corn Free
Gluten Free
Soy Free

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On account of the Agricultural Revolution and the many changes to the western diet, our bodies have experienced changes that sometimes can be detrimental because of a lack of adequate microbial exposure. That’s why using probiotics has become an essential part of maintaining a healthy gastrointestinal tract. Boosting the gut flora can help bring balance to the microflora and promote healthy immune and digestive systems.

Modern living has separated us from nature, and the hectic lives we lead often prevent us from eating an optimal diet. Even people who are considered to be in good health often lack a healthy microbiome. High-quality probiotics like Probiotic-3TM can introduce the right types of microorganisms into our microbiome.

Probiotic-3™ is a carefully designed formula that combines a blend of three bacterial strains that promote the health of the digestive system. Enterococcus faecium, a bacterial strain that naturally inhabits the human gastrointestinal tract, helps lower the gastrointestinal pH. It also helps block the growth of harmful bacteria by producing lactic acid as a byproduct of carbohydrate fermentation.

Clostridium butyricum is also a natural resident of the human gastrointestinal tract and breaks down dietary fiber into several beneficial nutrients, like butyric acid, which is an important source of nourishment for colonocytes (the cells of the lower gastrointestinal tract) and helps support our inflammatory response. Bacillus subtilis also supports the growth of E. faecium and C. butyricum as well as the growth of several strains of the beneficial Bifidobacterium species.

The three strains have been shown to help create an environment in the gut that is favorable to the growth of beneficial bacteria and unfavorable to the growth of pathogenic strains. As a result, Probiotic-3 helps promote the growth of the healthy bacteria already present in your colon. The bacterial strains have also been extensively studied as a combination and are used widely in Japan and across Asia.


The enterobacteria contained in Probiotic-3™ act in symbiosis and support healthy intestinal flora. Lactic acid and butyric acid-producing probiotics are unfavorable to the growth of pathogenic bacteria while promoting the growth of the beneficial Bifidobacterium strain.*

AOR™ guarantees that all ingredients have been declared on the label. Made without wheat, gluten, corn, nuts, peanuts, sesame seeds, sulfites, mustard, soy, eggs, fish or shellfish.
Adult Dosage

Take 2 capsules per day in divided doses between meals, or as directed by a qualified health care practitioner. Take at least 2-3 hours before or after taking antibiotics.


Consult your physician before use if you are pregnant, lactating, have a medical condition, or are taking any medication. Keep out of reach of children.

Consult a health care practitioner prior to use if you have fever, vomiting, bloody diarrhea, severe abdominal pain, discontinue use and consult a health care practitioner.


Streptococcus faecalis: Human strain
Clostridium butyricum: Human strain
Bacillus mesentericus: Potato skin

Main Applications
  • Digestive health
  • Immune system support
  • Inflammation response support

*These statements have not been approved by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Serving Size: 2 Capsules
Amount Per Serving
% Daily Value
Enterococcus faecium T-110
36 million CFU ‡
Clostridium butyricum TO-A
1.2 million CFU ‡
Bacillus subtilis TO-A
1.2 million CFU ‡

† Daily Value not established
‡ Colony Forming Units

Other Ingredients: capsule (hypromellose, glycerin and purified water), lactose, potato starch, polyvinyl alcohol, providone and sodium stearyl fumarate.

Contains: Milk.

Hamer HM et-al “ Review article: the role of butyrate on colonic function” Aliment Pharmacol Ther (2008) 27, 104–119

Chimura T. Ecological treatment of bacterial vaginosis and vaginitis with Bio-three. Jpn J Antibiot. 1998 Dec;51(12):759-63.

Horie H, Zeisig M, Hirayama K, Midtvedt T, Moller L, Rafter J. Probiotic mixture decreases DNA
adduct formation in colonic epithelium induced by the food mutagen 2-amino-9H-pyrido[2,3-b]indole in a human-flora associated mouse model. Eur J Cancer Prev. 2003 Apr;12(2):101-7.

Huang YF, Liu PY, Chen YY, Nong BR, Huang IF, Hsieh KS, Chen KT. Three-Combination Probiotics Therapy in Children With Salmonella and Rotavirus Gastroenteritis. J Clin Gastroenterol. 2013 Apr 29.

Rolfe RD. The role of probiotic cultures in the control of gastrointestinal health. J Nutr. 2000 Feb;130(2S Suppl):396S-402S.

Seo G, Akimoto Y, Hamashima H, Masuda K, Shiojima K, Sakuma C, Sasatsu M, Arai T. A new factor from Bacillus mesentericus which promotes the growth of Bifidobacterium. Microbios. 2000;101(399):105-14.

Shimbo I, Yamaguchi T, Odaka T, Nakajima K, Koide A, Koyama H, Saisho H. Effect of Clostridium butyricum on fecal flora in Helicobacter pylori eradication therapy. World J Gastroenterol. 2005 Dec 21;11(47):7520-4.

Song ZF, Wu TX, Cai LS, Zhang LJ, Zheng XD. Effects of dietary supplementation with clostridium butyricum on the growth performance and humoral immune response in Miichthys miiuy. J
Zhejiang Univ Sci B. 2006 Jul;7(7):596-602.

Tsuda Y, Yoshimatsu Y, Aoki H, Nakamura K, Irie M, Fukuda K, Hosoe N, Takada N, Shirai K,
Suzuki Y. Clinical effectiveness of probiotics therapy (BIO-THREE) in patients with ulcerative colitis refractory to conventional therapy. Scand J Gastroenterol. 2007 Nov;42(11):1306-11.