This 2017 systematic review and meta-analysis evaluated evidence from intervention trials on the effect of consuming tomato products and lycopene on markers of cardiovascular (CV) function. 21 publications were included and were meta-analysed. Overall, interventions supplementing tomato were associated with significant reductions in LDL-cholesterol, IL-6, and improvements in FMD; while lycopene supplementation reduced systolic-BP.
Cheng HM, Koutsidis G, Lodge JK, Ashor A, Siervo M, Lara J. Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis. Atherosclerosis. 2017 Feb;257:100-108. doi: 10.1016/j.atherosclerosis.2017.01.009. Epub 2017 Jan 13. PMID: 28129549.