The authors investigated the therapeutic value of L-Proline (Pro), a nonessential amino acid against oxidative stress cardiovascular disease (CVD). Findings suggested that Pro protects against MI injury at least partially via redox regulation, highlighting the potential of Pro as a novel therapy for ischemic HF caused by CHD.
Wang J, Xue Z, Lin J, Wang Y, Ying H, Lv Q, Hua C, Wang M, Chen S, Zhou B. Proline improves cardiac remodeling following myocardial infarction and attenuates cardiomyocyte apoptosis via redox regulation. Biochem Pharmacol. 2020 Aug;178:114065. doi: 10.1016/j.bcp.2020.114065. Epub 2020 May 31. PMID: 32492448. https://pubmed.ncbi.nlm.nih.gov/32492448/