This review from 2020 focused on available data relating to the role of proline (Pro) in collagen biosynthesis and cellular metabolism. It suggests that Pro availability determines the rate of collagen biosynthesis and demand for Pro in fibroblasts is predominantly met by conversion from Gln.
References:
This review from 2020 focused on available data relating to the role of proline (Pro) in collagen biosynthesis and cellular metabolism. It suggests that Pro availability determines the rate of collagen biosynthesis and demand for Pro in fibroblasts is predominantly met by conversion from Gln.