From 2021, this block randomized, double-blind, parallel-arm placebo-controlled trial was designed to assess the efficacy of P. niruri on the liver and renal function parameters, total oxidant and antioxidant levels in alcoholic hepatitis patients in comparison to placebo over a 4-week period. 71 patients were allocated into treatment and placebo arms. A 4-week administration of P. niruri in mild-moderate alcoholic hepatitis patients showed an improvement in the total antioxidant levels with an appetite stimulant activity compared to a placebo.
References:
Sowjanya, K., Girish, C., Bammigatti, C., & Prasanna Lakshmi, N. C. (2021). Efficacy of Phyllanthus niruri on improving liver functions in patients with alcoholic hepatitis: A double-blind randomized controlled trial. Indian journal of pharmacology, 53(6), 448–456. https://doi.org/10.4103/ijp.IJP_540_20
