In 2021 this study investigated the efficacy and safety of a combined soy and hop extract on postmenopausal symptoms. Seventy-eight women with moderate or severe menopausal symptoms were recruited for this 12-week, multicenter, randomized, double-blind, placebo-controlled trial. After 12 weeks the treatment group scores decreased by 20.61 points compared with 14.80 points in the placebo group (p < 0.05). Fatigue, paresthesia, arthralgia and myalgia, palpitation and vaginal dryness significantly improved more in the treatment group compared with the placebo.
References:
Kim, H. I., Kim, M. K., Lee, I., Yun, J., Kim, E. H., & Seo, S. K. (2021). Efficacy and Safety of a Standardized Soy and Hop Extract on Menopausal Symptoms: A 12-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Journal of alternative and complementary medicine (New York, N.Y.), 27(11), 959–967. https://doi.org/10.1089/acm.2021.0027