This randomized, double-blind, placebo-controlled clinical study from 2015 showed that MS patients receiving 500 mg/day of CoQ10 for 12 weeks presented with a significant decrease of inflammatory cytokine. CoQ10 also alleviates markers of CNS inflammation.
References:
Sanoobar M, Eghtesadi S, Azimi A, Khalili M, Khodadadi B, Jazayeri S, Gohari MR, Aryaeian N. Coenzyme Q10 supplementation ameliorates inflammatory markers in patients with multiple sclerosis: a double blind, placebo, controlled randomized clinical trial. Nutr Neurosci. 2015 May;18(4):169-76. doi: 10.1179/1476830513Y.0000000106. Epub 2014 Jan 10. PMID: 24621064.