This preclinical study published in 2019 presents insights into the importance of maintaining healthy biotin levels to prevent skin and hair changes often seen with zinc deficiency.
References:
Ogawa Y, Kinoshita M, Sato T, Shimada S, Kawamura T. Biotin Is Required for the Zinc Homeostasis in the Skin. Nutrients. 2019 Apr 24;11(4):919. doi: 10.3390/nu11040919. PMID: 31022908; PMCID: PMC6520690.