In this 2008, double-blind, randomized, placebo-controlled study on 75 osteoarthritis (OA) patients, the researchers evaluated the efficacy and safety of 5-Loxin in the treatment of OA of the knee over a 90-day period. 5-Loxin is a novel Boswellia serrata extract enriched with 30% 3-O-acetyl-11-keto-beta-boswellic acid (AKBA), which exhibits potential anti-inflammatory properties by inhibiting the 5-lipoxygenase enzyme. 5-Loxin reduces pain and improves physical functioning significantly in OA patients; and it is safe for human consumption
References:
Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee. Arthritis Res Ther. 2008;10(4):R85. doi:10.1186/ar2461 https://pubmed.ncbi.nlm.nih.gov/7603462/
