This 2019 pilot study, examined the effects of Longvida® Optimized Curcumin in patients with knee osteoarthritis. The study group (n=17) received the optimized curcumin 80 mg or curcumin from 400 mg capsules twice daily following meals for 90 days. The control group (n=25) received Ibuprofen (400 mg) once in the morning followed by placebo (dextrin) in the evening. Both groups showed a significant and comparable improvement in VAS and WOMAC scores in alleviating pain with Ibuprofen or optimized curcumin.
References:
Gupte PA, Giramkar SA, Harke SM, Kulkarni SK, Deshmukh AP, Hingorani LL, Mahajan MP, Bhalerao SS. Evaluation of the efficacy and safety of Capsule Longvida® Optimized Curcumin (solid lipid curcumin particles) in knee osteoarthritis: a pilot clinical study. J Inflamm Res. 2019 Jun 5;12:145-152. doi: 10.2147/JIR.S205390. PMID: 31239749; PMCID: PMC6559772.