This review from 2006 includes insights on all B vitamins and their role in energy production in the mitochondria. Authors outline preclinical evidence of the mechanism of action of biotin as a critical coenzyme. It is imperative for gluconeogenesis and fatty acid oxidation due to its role as a decarboxylase co-enzyme.
References:
Depeint F, Bruce WR, Shangari N, Mehta R, O’Brien PJ. Mitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolism. Chem Biol Interact. 2006 Oct 27;163(1-2):94-112. doi: 10.1016/j.cbi.2006.04.014. Epub 2006 May 1. PMID: 16765926.
