From 2012, this review looks at the effect of choline on liver function and fatty liver disease. Humans eating low-choline diets develop fatty liver and liver damage. Choline influences liver function, and the dietary requirement for this nutrient varies depending on an individual’s genotype and estrogen status.
References:
Corbin KD, Zeisel SH. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012 Mar;28(2):159-65. doi: 10.1097/MOG.0b013e32834e7b4b. PMID: 22134222; PMCID: PMC3601486.