From 2020, this comprehensive review outlines research related to the role of niacin in the body. Relating to neurotransmission, niacin plays an important role in managing calcium gated channels in neurons. Niacin channels are also widely distributed throughout the central nervous system. Further highlighting its importance, it has been shown that chronic niacin deficiency can lead to neurological symptoms, including depression and loss of memory.
References:
Tardy AL, Pouteau E, Marquez D, Yilmaz C, Scholey A. Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence. Nutrients. 2020 Jan 16;12(1):228. doi: 10.3390/nu12010228. PMID: 31963141; PMCID: PMC7019700.
