Definitions PEA (N-palmitoylethanolamide): an endogenous fatty acid amide synthesized and metabolized by cells that bind to cell receptors. It influences a multitude of physiological functions and has potent effects for a healthy inflammatory response and helps to relieve minor discomfort. Endocannabinoid System: A lipid communication network that has critical physiological functions and serves a vital purpose for our health and well-being through signaling processes, homeostasis and hormone regulation. Lipids and the ECS In 1929, scientists George Oswald Burr and his wife, Mildred Burr, discovered that omega 6 fatty acids were essential for health. This kicked off science’s interest into lipids, and
Vitamin B is actually a group, or complex, of several vitamins, each
of which is known by their specific number or name. Vitamin B12, aka
cobalamin, is one of this group that can itself be broken into four
different types: Methylcobalamin, Hydroxocobalamin, Adenosylcobalamin,
and Cyanocobalamin. Except for Cyanocobalamin, which is synthetic, they
are naturally found in animal products, including fish, meat, poultry,
eggs and milk products. They are essential for overall health and
vitality, and they contribute in different ways. Although each cobalamin
performs unique functions, they are often interrelated. A deficiency in
any one of them can lead to health problems, however, so let’s take a
look at the function of each in the body.
The forms of Vitamin B12 act as a co-factor in the body’s enzymatic processes. They facilitate reactions in the body, like a key turning on a car ignition. Each form of cobalamin is vital to different cellular processes. Because they are so important to key physiologic processes, a deficiency in them can lead to a variety of symptoms over time, from fatigue and increased cardiovascular risks to neurological issues, cognitive changes or depression and even poor balance.
Deficiencies can be caused by poor diet, impaired microbiota, or problems with absorption, due to diseases such as Crohn’s or Celiac, or the use of certain antacids called proton pump inhibitors. At particular risk are the elderly, vegans, smokers, people who use antibiotics frequently and those with pernicious anemia. Even certain genetic factors may influence B12 absorption. In the general population, it’s more common to see sub-optimal levels instead of a true B12 deficiency, but it can be difficult to correct if we don’t know which form of B12 we are lacking in.
The Power of Three.
Because of the inherent potential for issues with the absorption of B12, it’s advisable to take cobalamin in its most bioavailable forms. That’s why AOR presents Vitamin B12 in its three most active and bioavailable forms. By providing the three foundational forms of Vitamin B12 in its Tri B12 Synergy, AOR ensures that an appropriate dose of active and bioavailable B12 is present, for whatever B12 you may be lacking.