In the adult male study, healthy participants were given 300 mg MBP per day for 16 days and assessed for markers of bone loss. The results show a significant decrease in bone metabolism and bone loss. A decrease in urinary cross-linked N-teleopeptides of type-I collagen (NTx) excretion was also observed, suggesting that MBP promoted bone formation and suppressed bone resorption, while maintaining the balance of bone remodeling in healthy participants.
References:
Toba, Y., Takada, Y., Matsuoka, Y., Morita, Y., Motouri, M., Hirai, T., Suguri, T., Aoe, S., Kawakami, H., Kumegawa, M., Takeuchi, A., & Itabashi, A. (2001). Bioscience, biotechnology, and biochemistry, 65(6), 1353–1357. https://doi.org/10.1271/bbb.65.1353