The Truth About Red Yeast Rice

Red yeast rice is a brick-red powder food with medicinal properties and a long history. It is made by fermenting cooked white rice with a species of mold from the Monascus family, then drying the product and grinding it into a fine powder.
Red yeast rice has been a staple of Traditional Chinese Medicine and a food source for over a thousands years. In addition to the vibrant color and rich flavour, Monascus adds many beneficial molecules to the rice.

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Management of Cardiovascular Disease

WITH ANKASCIN – CLINICAL RESEARCH The key findings relevant to the use of Ankascin red yeast rice to manage blood cholesterol came from an experimental study in hamsters. Unlike other animals commonly used in research, hamsters develop many of the key characteristics of human cardiovascular disease when fed a diet that is high in fats and sugar15. The positive effects of monascin and ankaflavin in animal models led to human clinical trials to evaluate the ability of these molecules to manage blood cholesterol, blood pressure, and blood sugar. STUDY MONASCIN AND ANKAFLAVIN ACT AS NOVEL HYPOLIPIDEMIC AND HIGH-DENSITY LIPOPROTEIN CHOLESTEROL-RAISING

Frequently Asked Questions about Red Yeast Rice

Who Can Take AOR’s Red Yeast Rice with Ankascin? Ankascin is safe for most people; however, it should be taken with caution under certain conditions. Consult a healthcare practitioner if you are breastfeeding, taking other medications (including, but not limited to, cyclosporine, blood thinners, blood lipid-lowering medications, blood pressure medications or anti-diabetic drugs), if you suffer from liver or kidney disease, if you have received an organ transplant, or for use beyond 8 weeks. If you experience muscle pain, tenderness and/or weakness, discontinue use and consult a healthcare practitioner. Do not use if you are pregnant or plan to become

Safety of Ankascin

Red Yeast Rices Long-term use of statins, or of red yeast rice containing monacolin K, produces toxic side effects on the liver, kidneys, and skeletal muscle. These side effects are worsened by interactions with drugs that increase the biological activity of statins (see Table 1)45. Toxicity is a major reason why patients discontinue statin therapy, which in the absence of a suitable replacement leaves these patients at a high risk of heart attacks or strokes. Ankascin red yeast rice is statin-free, and has no reported side effects. Evidence for this safety comes from clinical trials, in which patients receiving Ankascin

Management of Alzheimer’s Disease

WITH ANKASCIN – CLINICAL RESEARCH Dr. Pan’s group recently completed a clinical study to evaluate the use of Ankascin to manage the symptoms of Alzheimer’s disease. HOW IT WORKS Antioxidants protect the body against the harmful effects of waste products produced by our cells. These waste products create a state known as oxidative stress, which is a major aspect of both cardiovascular disease and Alzheimer’s disease. Reducing such stress can slow the development of both disorders. Monascin and ankaflavin act as powerful antioxidants. Recent work from Dr. Pan’s lab showed that monascin prevents oxidation of amyloid beta protein, which is

Alzheimer’s Disease and Cholesterol

Several years ago, it was observed that patients with advanced cardiovascular disease were far more likely to have amyloid plaques in their brains than individuals without cardiovascular disease33. High blood cholesterol was also linked to the development of Alzheimer’s earlier in life34. Similarly, people who effectively managed their cholesterol with statin treatment were less likely to develop Alzheimer’s and similar dementias than individuals with high and unmanaged cholesterol35. Taken together, the data suggests a strong connection between cholesterol and Alzheimer’s disease. There are several possible reasons for the connection. Cardiovascular disease due to high blood cholesterol also affects blood vessels

Ankascin for Mental Health

Alzheimer’s Disease While most studies on red yeast rice supplements have focused on their use in managing cardiovascular health and diabetes, there is evidence to support beneficial effects of Ankascin on memory and overall brain function. Alzheimer’s disease is the most common cause of dementia, and affects about 300,000 Canadians over the age of 6532. The number of new cases in Canada has risen dramatically (over 20%) in the past 10 years. The main symptoms include memory loss, declining language skills, and loss of the ability to care for oneself. Unfortunately, since there is no cure, most treatment efforts focus

Mechanisms of Action

Ankascin works by normalizing cellular mechanisms that are disrupted in the previous clinical studies. High cholesterol, high blood pressure and high blood sugar are part of a group of related conditions called metabolic syndrome. This develops when the body loses the ability to properly manage its sources of energy, which are mostly fats and carbohydrates. Patients with this syndrome are at much higher risk for developing diabetes and cardiovascular disease. Many of the effects of metabolic syndrome are due to long-term inflammation and oxidative stress. However, both of which are reduced by monascin and ankaflavin. For instance, monascin reduces the

Ankascin 568-R

MONACOLIN K-FREE RED YEAST RICE Dr. Tzu-Ming Pan is an Emeritus Professor of Biotechnology at the National Taiwan University in Taipei. His research over many years focused on beneficial molecules produced by Monascus and many other plants and bacteria. His lab identified a strain of Monascus that did not make monacolin K, yet surprisingly was able to reduce LDL cholesterol in animal models. After several years of work, Dr. Pan and his group isolated two molecules from red yeast rice that were responsible for this cholesterol lowering effect. These molecules, named monascin and ankaflavin, are chemically very similar (see Figure 4),

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