Frequently Asked Questions about Red Yeast Rice

Who Can Take AOR’s Red Yeast Rice with Ankascin?

Ankascin is safe for most people; however, it should be taken with caution under certain conditions.

Consult a healthcare practitioner if you are breastfeeding, taking other medications (including, but not limited to, cyclosporine, blood thinners, blood lipid-lowering medications, blood pressure medications or anti-diabetic drugs), if you suffer from liver or kidney disease, if you have received an organ transplant, or for use beyond 8 weeks. If you experience muscle pain, tenderness and/or weakness, discontinue use and consult a healthcare practitioner. Do not use if you are pregnant or plan to become pregnant.

Which AOR Products Support Cardiovascular Health in Synergy with Ankascin?

Several AOR products act in different ways to help support cardiovascular health. The primary effect of Ankascin red yeast rice is to reduce blood levels of cholesterol and sugar. Oxidation of cholesterol can lead to the formation of plaques, even in individuals with healthy cholesterol levels. In this case, antioxidants will support healthy blood vessels by maintaining the cholesterol in its normal reduced state. Useful AOR antioxidants in this regard include Opti-Cholest, Acta-Resveratrol and Active Green Tea. Individuals who are also using statins to manage their cholesterol will have reduced levels of the essential antioxidant coenzyme Q10, leading to muscle pain.1 This can be managed by use of AOR’s Coenzyme Q10 supplement.

Are the Benefits of Red Yeast Rice with Ankascin Due Entirely to Monascin and Ankaflavin?

Many different molecules are produced by Monascus in the fermentation process that produces red yeast rice, and many of these may contribute to the beneficial effects of this supplement. These molecules include unsaturated fatty acids, pigments (monascin and ankaflavin are yellow pigments), and phytosterols. Many of these have positive biological activity. For instance, the red pigments monascorubrin and rubropunctatin are effective antibiotics2, and may reduce blood cholesterol through separate mechanisms3.

What is the Ideal Dose?

The recommended dose of one to two softgels per day is based on evidence from clinical trials that 110-220 mg/day were sufficient to see beneficial effects. Consult a healthcare practitioner before exceeding this dose.

Which Drugs are Safe to Take Along with Ankascin Red Yeast Rice?

There are no known drug interactions involving Ankascin. However, one should seek the advice of a healthcare practitioner to discuss their own individual situations.


1. Tan, J. T. and Barry, A. R. (2017). Coenzyme Q10 supplementation in the management of statin-associated myalgia. American Journal of Health-System Pharmacy 74: 786–793 able

2. Martínková, L., Patáková-Jůzlová, P., Křen, V., Kučerová, Z., Havlíček, V., Olšovský, P., Hovorka, O., Říhová, B., Veselý, D., Veselá, D., et al. (1999). Biological activities of oligoketide pigments of Monascus purpureus. Food Additives and Contaminants 16: 15–24

3. Campoy, S., Sierra, S., Suarez, B., Ramos, M. C., Velasco, J., Burgos, J. S. and Adrio, J. L. (2010). Semisynthesis of novel monacolin J derivatives: hypocholesterolemic and neuroprotective activities. The Journal of Antibiotics 63: 499–505.

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