Estrogen, Serotonin and Discomfort

Discomfort is a subjective perception influenced by numerous factors. Sensitivity to discomfort can be vastly different from one person to the next. Some influences on discomfort sensitivity levels include psychological and neurobiological factors, but gender and sex hormones also play a very particular role. Researchers have found that there are actual differences in how men and women experience severity of discomfort, because sex hormones are involved in discomfort transmission and sensitivity. Specifically, estrogen is linked to visceral discomfort sensitivity. That is, discomfort that is diffuse and poorly localized. In multiple disorders that involve visceral discomfort, such as gastrointestinal disturbances and

P.E.A.k Relief

By Dr. Traj Nibber The endocannabinoidome (eCBome) is a broader and more appropriate term than the old endocannabinoid system (ECS), and incorporates the more recent research into this fascinating area. What is the eCBome Briefly, eCBome is a protective, and communication network that exists all over the body, and interacts with hormonal, nervous, immune, endocrine, microbiome, and other systems of the body. The eCBome plays a major role in the health of many organs of the body including; the reproductive system in both males and females, hormonal system, kidneys, liver, gut microbiome, heart and circulatory system, nervous system, skin among

The Mighty Molecule: The Role of PEA in the Endocannabinoid System

Definitions PEA (N-palmitoylethanolamide): an endogenous fatty acid amide synthesized and metabolized by cells that bind to cell receptors. It influences a multitude of physiological functions and has potent effects for a healthy inflammatory response and helps to relieve minor discomfort. Endocannabinoid System: A lipid communication network that has critical physiological functions and serves a vital purpose for our health and well-being through signaling processes, homeostasis and hormone regulation. Lipids and the ECS In 1929, scientists George Oswald Burr and his wife, Mildred Burr, discovered that omega 6 fatty acids were essential for health. This kicked off science’s interest into lipids, and

What is Magnesium?

Magnesium is an essential mineral involved in over 300 metabolic/enzymatic reactions in the body. Its name comes from the district of Magnesia in Greece, an area that contains a vast amount of magnesium ore. Magnesium plays a key role in cardiovascular health (normal blood pressure and steady heart rhythm), bone health, the transmission of nerve impulses, immune function, and the production of cellular energy. Most people are deficient in magnesium, but are totally unaware of it. This is further compounded by low levels in foods and low-quality supplements. While there are blood tests that can assess magnesium levels in the

Curcumin Protects Against Heart Disease: New Research

Curcumin is the bright orange colored major active compound extracted from the spice turmeric. Turmeric is a widely used condiment in South East Asia and is a favoured component of Indian curries. The spice has been used for centuries in both Indian and Chinese cuisine as a flavoring and coloring agent and as a food preservative. Turmeric in Ayurvedic and traditional Chinese medicine (TCM) Turmeric is a key ingredient in many frequently used Ayurvedic and TCM formulas. In fact, turmeric is the main ingredient used by almost every Indian household for ailments such as digestive disorders, liver complaints, parasites, diabetes,

A History of Turmeric

Turmeric possesses a rich, deep, bright orange/golden color due to its high content of pigments known as curcuminoids. These beautiful pigments are known as fluorochromes, meaning they are fluorescent! This explains why turmeric has been used as dye, a coloring agent in paint, and why it stains so easily. These pigments are truly unique and very special, seeing they are mostly responsible for turmeric’s therapeutic activity. There are three active curcuminoids present in turmeric: curcumin, demethoxycurcumin (DMC), and bis-demethoxycurcumin (BDMC), with curcumin being the most concentrated. It comprises approximately two thirds of total curcuminoids, while the other two comprise the